Roger Castells-Graells
Roger Castells-Graells
Home
Publications
Experience
Contact
3
Rigidified Scaffolds for 3 Angstrom Resolution Cryo-EM of Small Therapeutic Protein Targets
We use molecular engineering techniques to rigidify an imaging scaffold, based on a designed protein cage, to the point where 3 A resolution can be achieved with cryo-EM, even for very small proteins.
Roger Castells-Graells
,
Kyle Meador
,
Mark A. Arbing
,
Michael R. Sawaya
,
Morgan Gee
,
Duilio Cascio
,
Emma Gleave
,
Judit É. Debreczeni
,
Jason Breed
,
Chris Phillips
,
Todd O. Yeates
PDF
Cite
BioRxiv
Cite
×